RE: 22-250 or .223 ranges
The only honest reason people claim that the .22-250 has a longer range than a .223 is because of the guns they're typically chambered in...most guys that love the .223 for varmints have AR-15's, or at least are thinking about them, while guy's who claim the .22-250 as the ultimate cartridge are usually thinking about Bolt action heavy bbls.
In that comparison, yes the .22-250 has a longer range, however, pack them both into the same model of rifle and you've got two loads so close in performance (ballistic and field) that you nor your game will ever know the difference.
My loyalty stands with the .22-250, as I've been shooting it for varmints longer, however, I do tend to take my AR out more often than my varmint rifles!!!