i've been chasing moose most my life and the 30-06 with 180 grain is perfect!i got a big bull this year with a 270 150 grain bullet but i had to shot him 7 times.5 from the tree stand,all in the foreshoulder at about 220 yards,and twice when i was walking up to him.knocked him down twice but these animals are TOUGH!shot him twice and he still kept coming towards the mare in heat.