RE: handgun hunting
I hunt with a 454 SRH . The 3 SRH cal choices are 44 , I would use either FED hardcast load I or My favorit load REM 44 mag 275 gr corelock ,I would sight dead on at 75 yd with either load ,then hold dead on to 100 yd
454 any load , I would chose the Win. 250 gr load at 1300 fps ,I know it is not full power but to 100 yd you don't need more and a lot less noise and recoil .again sight dead on at 75 yd
480 ruger ,I have a friend that loves the 325 gr Hornady load again I would sight dead on at 75 yds