I have always be very well served with the federal premium loading of 100gr Sierra gameking bT. Between my sister, and I that load or a handloaded duplicate have taken close to 20 whitetails in the last 8 years. Never had a deer go more than 20 yards and never had to shoot one twice. I have had double shoulder penetration on 3 of them. From ranges of 75-280 yards it has worked like a champ. Two of these deer feild dressed over 150lbs, on was a 168lb 7pt and the other was a 175lb old dry doe. The doe was just plain huge. The average deer in my hunting area dressed out from 120-135lbs.