I'm looking for a new 100-300+ yard target rifle, and I've been considering everything from the .223/.22-250 range, to the .243/.25-06 range. I was not aware of barrel-burning issues and the like, so that may need to be a consideration... but my goal is to get a very accurate, preferably flat-shooting (so there's not too much bullet rise if I'm shooting at 100 yards and I'm sighted-in at 150) rifle without too much recoil. But now I guess I should add "long-lasting / non barrel-burning" to my wish list.
Are the .243 and .25-06 good target alternative to the .223 and .22-350 for my applications? Does anyone know a resource for researching specs on various rounds - such as velocity, bullet rise/drop at given yardages, etc.
Anything else I should be considering in my decision?

By the way, whatever the caliber, I seem to be set on the Sako 75.

Thanks for your help,

- Aaron