I would get a 270-Winchester barrel for that TC Encore. The 270 is just enough of a step up in calibers to fill the Medium/large game gap. The 243 IMHO is a great varmit/small/medium game rifle.
With the 270 you will have a gun that you can hunt Whitetail, Mule deer & Antelope with confidence. The recoil is mild & the knock down power is plenty.
IMHO I think the 25-06 is too close to the 243? I think a person should space out there calibers. I am saying this because I wish I would have spaced out my calibers. If I could do it again? I would own a 243, 270 & 300-win mag.