Yes. If you sight in at 25 yards, you can pretty well be assured that your bullet will land on paper @ 100 yards so you can finish zeroing. However, since all rifles are individuals, you cannot COUNT ON the bullet landing within any predictable parameters by use of drop tables, trajectory charts, etc. In additon, any deviation in elevation is likely to be mimicked to an even greater degree by windage deviations! 25 yards is a good place to start shooting. It will save you ammo, but you really MUST finish your sight adjustment drill at a distance of at least 100 yards, and it is desireable to do confirmation of zero shooting at a greater distance than that. I am now limited to 200 yards myself, but used to do this windage check shooting at 400 yards. You'd be amazed at how far off a bullet that is dead on center @ 100 yards can be @ 400! On a windless day!!