a 180 grain "Core-lokt" in the lungs is better than any "Premium" bullet in the paunch.
I think Colorado Bob summed it up pretty darn well.
I shoot reloads, my bullet of choice is the Nosler Partition.
My father shoots a 40-year old 30-06 rifle with 180-grain round nose Remington Core-lokt ammo. He has killed a ton of elk & deer over the years with this same rifle & ammo.