I will also add to YES but if you’re looking at going from 100 grain to 125 grain there shouldn't be any difference in flight unless you’re pushing the limits of your set up now.
If that be the case and the arrows act differently try 2314 same weight per inch but stiffer.
Next FOC.. yes it affects but out 25 yards you wont notice the difference but the same could be said for a long 100grain head (thunderhead) and a short (rocky) your arrow will start dropping sooner . I am no speed freak and believe the 240/250 fps range is perfect
For any hunting bow...the arrows are heavier and they WILL QUITE THE BOW DOWN...
Even in carbons they are making the hunting weight 8.5 up 12....grains per inch
And a heavier arrow is easier to tune.....