H110 (identical to Win296) works just fine with those 158gr Hornadys. I'll have to double check my data, but I believe my best load-out for 158gr XTPs out of my 4" Ruger Security Six is 16.0gr (but let me double check that before taking it as gospel). It's a "kicker", with lots of flame - very impressive to watch!

For a hunting load, I think I'm using 14.0gr of 296 with the 180gr Speer Gold Dots with the filled lead center (again, I'll verify that charge once I get home).

I will say that the H110 (296) is not a real good choice for lead plinking loads though. 7.0gr of Hodgdon Universal Clays is my load for 158gr LSWCs - with Win231 also giving good accuracy results at a lower powder charge. In fact, 231 is a pretty good choice for both .38Spcl & .357Mag loads with all bullets & weights.

BTW..................give those .357 loads a GOOD crimp when you load them.