Took me a few years to finally get used to one, but now I don't forsee ever shooting off the string again. Way too many advantages for the minimal speed loss, and with a peg style release like a Scott Rhino you often don't have to give up anything in speed and can maintain your draw length (and same anchors)

I've never found a loop to be a hindrance in the woods, and I hunt on the ground where often I get deer super close before I ever see them...I hookup as they walk behind a bush or tree, and go from there. In a treesatnd I don't see how this could ever be an issue for someone who has gotten used to the loop and has a decent release aid with a small jaw or peg.