I have to agree with most on here. Passthrough's are not a definite by any means. Too many variables come into play when shooting at an animal.

On the other hand, a well tuned hunting setup should yeild a passthrough in most cases if the shot placement is correct. I personally have never had any issues with passthroughs on my past dozen or so animals I killed. But these were all well placed shots. My setups don't yield particularly high KE compared to some. 65lb, 28" draw and a 400 grain arrow shooting in the mid 260's has blown through all of the deer I've killed in the past few years.

I have a cousin who blew completely through an elk at 30 yards with almost the exact same specs as myself. You do not need ultra high KE to kill even the largest game.