Hoyt's limb deflections are designed to match a specific cam size on each bow.

E.g. Cam size 5 will require X deflection limbs to make 70 pounds. Cam size 5 will need Y deflection limbs to make 80 and Z to make a 60 pound peak.

If you switch to a number 4 or number 6 cam (even with appropriate string and cable lengths), it will cause a change in peak poundage, as that cam size was matched at the factory with the proper limbs to make a particular weight.

Twisting strings or cables to gain back or lose poundage is not the solution as this will throw the bow out of spec by altering the position of the cams, thus affecting limb pre-load, brace height, AtoA , etc.