Below are some loads using a 180 grain bullet.
Data came from the Nosler Reloading Manual 5th Edition (most recent)

300 Weatherby
IMR4350 76 grains Muzzle vel. 3088 fps
RL19 79 grains Muzzle vel. 3198 fps
IMR4831 76 grains Muzzle vel. 3028 fps
RL22 80 grains Muzzle vel. 3132fps
AA3100 77.5 grains Muzzle vel. 3050 fps
IMR7828 84.5 grains Muzzle vel. 3185 fps
H1000 89 grains Muzzle vel. 3146 fps
H870 92 grains Muzzle vel. 2970 fps

I load the 180 grain Nosler Partition in my .300 RUM.