Nope I'd say look at 165-180 grain as your one only bullet if you have your heart set on only using one for all game. I 'd look at Trophy Bonded, Nolser Part, Barnes X, Speers Grand Slam, Win. Failsafes or bonded polymer bullets like: Nosler Accubond or Hornady Interbond.

Also I think your confusing grain size as the determining factor for what to use vs game. The old days maybe so but today we have the luxury to have bullets(like mentioned above) that are constructed in a way to take advatange of smaller diameter bores/grain size and will result in equal and many cases more superior results. The determining factor is construction, what you look for in a deer bullet is very different than an elk or moose bullet, as the body composition is much different in the game. Almost any bullet will punch clear through a thin skinned animal like a deer, but elk and moose are both larger in body size(to soak up energy and impede progress), thicker skinned and larger bones, thus it is important to find a bullet that will create a wound channel, but also stay together long enough to punch into the vitals and possibly thorugh the opposite side. Good rule of thumb strong the game the strong the bullet construction needed to get the job done. Now some will use these bullets for deer which will work but can also cause problems such as limited expansion, less shock & less of wound channel=less blood on the dirt. Personally I use different bullets/construction because I want different effects on the game I am hunting. For example on deer I want rapid expansion and will use a Nosler Ballistic Tip or similar. However for Elk or Moose I want controlled expansion and penteration so I will use a win. failsafe, Nosler Partition, Trophy Bonded, Barnes X, etc. It boils down to personal preference and experience.

I think the more reasons or excuses you have to punch paper the better, practice will make improvements to your in field expeditions and will lead to more confidence, ability assesment, limitation setting and ulitmately success. The fact you have to monkey with your scope is good b/c it keeps you familar with how to do so if you incure a scope bump that requires some fine tuning, I honestly can't tell you how many times others have said so to move it down I need to do what??? Sounds stupid but practice and T&E is a good thing IMHO. Not to mention a guy will spend the money to buy and outfit his rifle only to pull it out for one trip a year, doesn't really make sense...your at the range so what is wrong with adjusting the hairs a little now and then.

Best of luck and enjoy playing with your rifle