Every rifle has a load it likes best, and it's a matter of experimentation to find it. The 30-06 gets all it can get out of a 22" barrel, so moderately slow powders work best. The 06' isn't finicky to load, and lots of powders work well. I like H414, lit be CCI250 primers, and 150 or 165 grain bullet of your choice( for deer sized critters, although my wife has taken 5 elk with the 165). Sierra, Hornady, and Nosler all are good choices and will work well. Consult your loading manuals, and mind your overall length. Have fun...