i have used rifles calibered in .22 mag and .17 hmr

after careful consideration (bullet speed, killing power, accuracy,cartridge availability/ cost, yada yada yada)

i chose to buy the .17 hmr

these little varmint express bullets cruise at 2550 fps and i can tell you they are devestating on crows, rabbits, praire dogs, squirels, and a one shot kill on 3 coyotes. i have yet to test it over 100 yards but up to 100 i would take it over the .22 mag

just my 2 cents