Yep. That's my favorite way to shoot a compound, especially for hunting (good thing too, because my eyes can't see pins any more anyway). Of course, not with an MM, since that bow is way shorter than my draw length.

My compound is 46" axle to axle.
I generally average mid-270's on a 30 target 3D course, scored 10-8-5, and was an amateur staff shooter in that style for awhile. So, I guess you could say I've been fairly successful with it.