Now this is a tough one.
Trophy moose in Alaska would be awesome. Shooting a 60"+ plus bruiser would certainly be hard to beat, especially if you could add a grizzly bear ...........

Really big trophy whitetails are awesome looking. I would be totally bored hunting them from a treestand or over a food plot however.
But maybe a rut hunt using rattling ..........

Trophy mulies have been my quest for many years. I have a couple nice ones already. Hard to beat that feeling when you have been glassing for hours seeing nothing and then...

Trophy elk with a rifle during the rut is hard to beat. I have a couple nice elk already but really, nothing can compare to a big bull coming in silent and then when he gets within 40 yards of you he busts loose with..........

I pick the trophy muley hunt. Just something about the animal and the mountain country that I couldn't trade for any of the others.
Sitting up on a high vantage point at 10,000 feet as the sun comes up and glassing till your eyes are watering for that buck of a lifetime is where it's at for me.