The only advantage the 22-250 has over the 223 is tragtory. Most guys aren't good enough shot's to take advantage of that! 400 yards shots and beyond is where the 22-250 is suppose to shine, just wasted yardage.

223 will kill PD's, rock chucks, and even coyotes out to 350 and even 400 yards. It uses less powder, brass and ammo are cheap. You can put 20 rounds in your pockets. It's is easier on your ears. The barrel will last twice as long.

Do I shoot long range (400 to 600 yards)? You bet, but I jump up to the 22-243 (with 80 gr VLD bullets and a fast twist barrel), 243 or 25-06. They will buck the wind so much better than a 55 gr bullet out a 22-250.