25-06 is hard to beat, and the ammo is available here at lots of stores. Every gun store carries it and even the "Marts" sometimes.

It's a heck of a caliber. Head and shoulders above the 243 - due to bullet selection. The 120 grain Core-lokt will put any whitetail down, and the 80 grain ballistic tip will shatter any chuck. Either will do in a coyote...depending on what you want to do with the hide.