I did shoot a nice 6 X 7 bull in the neck about 20 years ago. The shot broke his neck and he went down in a heap. To this day that is the biggest bull I have taken.
But, I would not take that shot now, I would wait for a better shot. I was very lucky

I now bow hunt for elk every year and would only take a broadside or quartering away shot.
I do also hunt elk with my rifle, and would wait now for a better shot placement.
Camo