RE: 45-70 in Africa.
There was an article in outdoor life/F&S awhile back about bowhunting for elephants. The guy made a bad shot and the story didn't turn out too well for the hunters. A bad shot can be made with any big magnum and still have disasterous results.
I'll never have the priviledge of hunting in Africa, and I'm not a big fan of big magnums, but if I were given the chance to hunt something that not only has the potential to stomp me into paste but the inclination to, I'll be using the biggest artillery that I can shoulder.