RE: Changing Primers? Will Cause Pressure Diff?
Changing primers can make a difference on pressure. If you put a large rifle primer in a magnum case that suggests a magnum primer, then you have to back off the load alittle. Because the lr primer will burn the powder slower and you will have more pressure in the chamber. This can be a bonus for more uniform powder burn but it causes pressure and it needs to be handled with more caution. I'd say stay with whats recommend on rifles.
Pistols need all the powder burn they can get. It is okay as long as your not swelling cases. But I've learned that pistols tend to like loads that are not hot.