RE: Two calibers ... two elk.
If you get the correct shot angle, and if it is legal, I think you could kill an elk with a .22 rimfire. In fact about a year ago I read a story in the american hunter about a reporter that went on a caribou hunt. while there he met a native who made a living many years ago by killing polar bears and selling the hides and the skulls. HIs weapon, a .22 rimfire break action. this is true It says that he shot about 23-24 bears like this. He would shoot in the exact right spot from about 25 feet and the bear would drop in his tracks.