You can just flip a coin on this one. The 7mm-08 Rem can have better long range ballistics due to better ballistic coefficient and sectional density, but I doubt anything you shoot will know the difference. I have one of each and shoot them both. I favor the 7mm-08 because it recoils less. If I had to choose between the two for a deer cartridge I would go out and get a 260 Rem instead.