I have hunted in the West for more than 30 years, exclusively with a 7mm magnum, for a variety of game. Many of my friends shoot the caliber, but others shoot 30-06, 270, 280, 30 cal magnums. I never saw a deer. moose or elk shot with one that couldn't have been shot just as dead with another. Most of the differences are theoretical. Most misses I saw came from long distance shots made without proper support, so trajectory didn't matter so much. (Especially nowadays when we can use convenient rangefinders to train ourselves year round for better range estimation skills.)

One thing though about 7mm and other magnums. In built up areas (i.e. farming areas, not wilderness mountain country) I have had people remark about the noise my rifle makes. 30-06, 270, 280 make less fuss. This is especially true when you spend an afternoon in a back quarter doing some practice shooting.