Well, I'm going to get blasted for this, but I for one believe that velocity, distance, and bullet construction can and will have a effect on bullet performance. I've seen fragile bullets like the Hornady SST literally blow up inside 200 yards on deer. Better bullets have mushroomed as they should have beyond 100 yards, but while inside 100 yards, they just punched a small hole without ever expanding. My last 8 point was shot at 70 yards, broadside, with 150 grain Core-Lokts out of a 30-30 rifle. Deer dropped in his tracks and never moved. I have never had a problem with Core-Lokt bullets.

If I was going to use any bullet other than the plastic tip bullets inside 100 yards out of a gun such as the 7mm Mag, I'd aim so that one shoulder was taken out.