If the recoil doesn't bother you, I'd try 150g (3 pellets) and the 250g barnes expanders. These regularly shoot moa, and are hell on deer and antelope. I've never recovered a bullet even with shot out to 240yds. Expansion/pentration is awesome. It seems my disc rifle was made for this load. Interestingly enough, 100g (2 pellets) does not shoot particularly accurately and I have seen the load fail to exit on a big mule deer at 70 yards (shoulder shot).