You would never have to look past the cartridges based on the 308 case. 243, 260,7mm-08 and 308. Having said that though my all time favorites are the 308 and the 6.5x55. I have taken more deer with these two than all the others I have used combined. My new favorites, (new to me) are the 250-3000, 257 Roberts and the 280. I can't be faithful to one caliber either The 25-06 would have to be one of the best deer calibers going as well.