I have traveled to Newfoundland 5 times. The trip there is fairly easy traveling on major highways and the TransCanada. The ferry ride over/back can be tricky depending on wind. Sometimes there are delays. If you are driving to a camp you are most likely driving on gravel roads, sometimes rough ones. Nothing a 4x4 truck can’t handle.
I have had 3 Caribou and a moose processed there. Can’t remember how much the caribou were, but the moose (a 2 year old bull my daughter shot) was about $450.