Strongly considering a .280 AI.
My feelings for that 270/.30-06 case, the 280ai probably gets the most out of it. and honestly if I'm hunting something that the .30-06 would do better than the 280, I'm going to just be using a bigger magnum probably.
speaking of 0-500yds... with all this BC talk...it's my understanding that high BCs really don't start to take over until after 500yds, so unless that's a critical choice in an upcoming hunt....