Not with a .23 but I have shot both with a 7mm TCU which is basically a .223 necked up to 7mm. For me a .223 just doesn't have enough bullet weight for big game. I know it will work on perfectly broadside shots but not every shot is a perfect broadside shot and I want at least 100 grs of bullet so I know I can break through bone. I have however shot men with the 5.56 (ballistically identical to the .223) and that would be about the same size as most deer. It caused graphic wounds but not what I want in a hunting round.