No, a 22 doesn’t shoot flatter than a 450 Bushmaster. I think you’ve been mislead by a lot of speculative conjecture from fools.

A 22 Long Rifle will push a bullet around 1100fps, whereas your Bushmaster with standard loads should be pushing 1800-2200fps, with an inherently better ballistic coefficient.

It’s great you enjoy your 450 Bushmaster, but you’re displaying an obvious bias. Many, many cartridges will deliver fast kills on game, and the 450 Bushmaster certainly is not the least of them - implying anything with less energy would slip below some “cut off limit.” If you’d come in talking about your actual negative experience with the .350 Legend, or similar cartridges like a 357max, 38-55, 357mag rifle, 357/44 B&D, .358 Winchester, .375 win, etc, and contrasting those against your experience with the .450bushmaster, you’d have an objectively defensible case. But just saying “the 450 Bushmaster is more powerful, and I like it,” isn’t really any evidence the .350 Legend won’t perform well.

Your 125 yard limit assertion, which is what I questioned, remains to be undefended by your assertions of superiority in the 450 Bushmaster. When “enough is enough,” then “more enough” isn’t really anything.

Folks have been killing game with cartridges similar to the 350 Legend for over a hundred years - if it were insufficient for the task, we’d have figured that out a long, long time ago.