Hornady has data for T/C pistols as well as rifle data and it basically the same some powders show 1/2 gr. less for one or the other. Just start on the low end like you would with any load work up.
I only load for a rifle and 120 Nosler BT's with 45 gr. Varget is my favorite but I did use 47 gr. H4350 and 140 gr. Barnes TSX bullets for a bunch of deer.