All said above is why I'll only use 00 buckshot for home defensive use. Someone here questioned my decision one day on how I could justify that vs hunting. I asked them to look around themselves as they typed and pick out the longest range they could find. In my fairly large home right now it might be 30 feet, 45 feet would be pushing it from any angle. Does it work on deer? I've seen a few shot with it at 25+ yards but none were definitive like a well placed rifle shot.
REM7600