Bronko, I shoot the 280Rem and my grandson shoots the 7mm-08. Not much difference between the two. Yes, the 280 will hold more powder thus may kick a little more and give you maybe a couple more hundred FPS, but no deer would know the difference. My grandson shoots a Ruger All American in 7mm-08, yet I shoot the Rem700 in the 280. Because of the weight, my grandson says the 280 kicks less. I always compare the 30-06 between the 308. The difference is only about 100FPS or so between the two shooting the 150-165gr bullets.