I myself don't even try to estimate yardage past 200. That's what laser range finders are for. Or Mil Dot calculations to get reasonably close, better than straight eye guesstimation.
homers_brother, my normal range is within 100 yards since I, 75% of the time, am using a sidelock muzzleloader. The few times I have even attempted longer range shots were out west, Colorado to be specific, at animals I knew I wasn't going to be able to get up on due to time limitations. As in finding them in a feeding meadow but they are about to head out to bed. Never went cross canyon on a shot for the very reason you listed. I'm only a little stupid not completely brain dead.