So you're saying my 7mm Rem Mag which has taken a huge number of mulies shouldn't be used on mulies? Nor should the good old 30-06, which predates both the 270 and the 25-06?

As to the OP, good mule deer hunts can be had in a number of western states. I am a CO native but now live in TX. My nod would go to CO for mulies but I have also taken them in WY, MT, UT, and NE. It really comes down to what you want and when you want to hunt. Different states have different season. It may also be worth your time to look at the TX panhandle. They take some really good mulies there by Amarillo but you would have to be guided since it is private land. I believe the going rate for mule deer hunts there are about $3500.

One piece of advice for a first time mule deer hunter is don't expect a monster with a 30 inch spread. Such deer have never been common. The spread on the ears of a mulie is about 22 inches so if a buck is carrying 4 points to a side and is wider than his ears then I'd shoot it if it was my first hunt. Such a buck makes any whitetail look small since the rack will probably be as tall as it is wide. Big old mossy horned deer of any species don't come around that often no matter what the magazines say.