This one would be a relatively easy choice for me - any well built 7mm, be it a WSM (preferred) or long action. Throw a Burris Eliminator on there for confident shooting at any practical range with any load. 139 SSTs for small game, 168 Hunting VLDs for almost anything and then a big Swift A-Frame for Elk/Moose/Bear. Nothing that rifle can't do (for typical North American game at least) be it big or small, close or far. A close second would be a .308 shooting the 178 ELD-X or Nossler Partitions anywhere from 140-180 grains (hand loaded) tailored to the game being hunted.