I have owned a .25-06 in the past and it is a good cartridge. I currently own a .260 and it is also a good cartridge. Personally I believe the felt recoil of the .260 is a little less. It offers very good medium game performance at a price of little recoil. I am very happy with the .260 and highly recommend it to others.

Good luck with your decision!

P.S. The .260 can be had in some very nice short action rifles which is not true of the .25-06.