Hogs ain't rhinos. Any good 150 grain .30-06 bullet is capable of killing a 350 pound wild hog. i personally prefer the 180 grain bullets for big hogs. Nearly any 180 grain .30-06 bullet is capable of penetrating both "shields" on a 350 pound hog.
Most of my hogs are killed with a .50 caliber muzzleloader. This big boar was killed with a saboted .452 SST bullet. Bullet penetrated both shields and was found under the skin on the opposite side. The bullet path measured 19".
Hog went about 200 yards when shot.