I'll be there at 6 o'clock...
No matter the target or the firearm, I want to be able to see my target. I never use a "cover hold" sight picture. My 6 o'clock might be deeper on some firearms than on others, for example, my hold will be lower for a match Service Rifle or a Bullseye pistol where I know I will have an aiming black than it would be for a hunting rifle where I'll be placing the sights tightly beneath the POA.
The only sights with which I ever use a "cover hold" are red dot sights and scopes. Put the dot or the crosshairs exactly where the bullet should go, and squeeze. The only exception to this is a pointed reticle like the German No. 1 reticle or the triangle dot in the Trijicon RMR, where I place my POA right at the tip of the reticle.