I stumbled across this load when I was in high school, forget if it was a NRA reduced-range HP match load or where exactly, and I forget the bullet it was SUPPOSED to use, but I've loaded over a million of these since then (literally, as depressing or exciting as that might sound) and shot them through hundreds of AR-15's and bolt rifles.
If 27.3grn Varget under a 50grn V-max doesn't shoot well in your rifle, your rifle has a problem.
Of course, this assumes your reloading practice is sufficient to size, charge, seat, and crimp consistently.