I killed my then largest buck on opening day in 2012 with my 270 using a 130 grain Nosler Ballistic tip. He initially came within about 40 yards of my blind after a doe, but in my excitement I knocked my camera tripod over into the side of the blind. He heard and saw that, and consequently turned around to run away. I blew two grunts on my grunt tube, which caused him to stop at a little less than 100 yards, turn around to face me, and stomp at me. The only opportunity I had was a full frontal shot, so I took it. He turned tail again and ran about 75 yards, but he was dead by the time I got to him. I never found the bullet while field dressing him, but damage to the stomach suggested the BT ended up either there or somewhere in his intestines.

FWIW, I also shot a coyote with a BT back in the summer of 2014. That coyote made the mistake of running around our horse pasture. I grabbed my 270 the first time I saw it, and when it came out again I killed it at 245 yards. You couldn't really tell where the entry wound was, but there was a definite exit wound about two inches long on the far side.