It definitely can. There are a bunch of factors that affect draw length from one bow to another. On my Mathews MR8, the draw length even changes when you make draw weight adjustments. Thats why, when I set up a new bow, I usually use my measured draw length as a starting point. Then I'll take some time to shoot it and make any adjustments necessary. I don't mess with tuning or sighting in until I'm comfortable with draw length.