Yup...
I always want to be able to call myself a rifleman, but if I'm anything, it's a handgunner.
I've taken deer with revolvers, bolt action specialty pistols, break action pistols, muzzle loading pistols, cap & ball revolvers, and semiauto pistols. Took my first deer with a handgun about 25yrs ago, a Smith in .357mag. The rest is history.
I'm still working on completing my "ideal deer hunting revolver" in time for this season, a Ruger Redhawk in .357/44 B&D under a Leupold 2.5-8x. Working on some semi-ortho grips for it right now, and working on my 250yrd groups for this fall.