I read in one of Sam Fadala's books year ago, that it is the "revolutions per second" (RPS) that stabilizes a bullet/ball. Therefore, it is a combination of velocity and twist rate that stabilize. This is why modern bullet may shoot fine to 400 yards but begin to tumble/key hole as it slows down at 500 yards. It is still spinning but forward velocity is slowing way down. Different for every bullet. You have likely seen a thrown football do this exact same thing.

Velocity is affected by powder type, powder charge, weight of bullet, length of barrel, and maybe even a few more things.

Twist rate is affected only by twist.

Since a pistol barrel is very short it is hard to get much as velocity. So to stabilize a given bullet you have to increase the rate of twist for that short barrel to stabilize that bullet/PRB.

That's about how Fadala explained it. And he is correct.

And yes, you can push a PRB or conical so hard that it "strips" off the rifling. It is a fact. Bronco22000 makes some very good points.