If you want to shoot Pyrodex at 200 yds. You'll have to have it shoot high at 100yds, or use holdover at 200yds.

Pyrodex is only slightly more power than the weaker real BP powder. Switch up to T7, or BH 209 for less holdover. A BDC scope would help too.

Even 150gr of Pyro will shoot low at 200yds if you have it dead on at 100yds. It's not a 30-06.