IMO if you can figure out a way to reliably kill them dead, you are good to go. Just putting a bullet in them isn't actually the task, putting them down is.
I shot a really old Doe awhile back. She was really sneaky. I'd hunted this large lease for years and had never seen her before and she was right in the middle of a 3200 acre lease.
She was obviously on her last legs, she was skin and bones. I put her down, just so she wouldn't get sick and possibly spread it around.
I found a bullet lodged in her lower jaw, it had been in there for a long time. It was abscessed and the bone was dissolving. Stuff like this just makes me sad.
The military taught me to put a round in a man sized target at 500 yards. I taught myself how to put it in their ear.
All you guys are just novices anyway, we used to chop off 2X4's at 1200 meters just to get sighted in. Tankers have bigger guns.
